The recommended dosage of vitamin B12 varies depending on the type of bariatric surgery performed
Therefore, it is not appropriate most -- especially those who are pregnant, breastfeeding, have active cancer, or certain metabolic conditions
Whilst B12 injections (hydroxocobalamin) are licensed NHS medicines for treating confirmed deficiency states such as pernicious anaemia, lipotropic injections lack MHRA marketing authorisation and robust clinical evidence
Dose optimization, dietary adjustments, and exercise modifications typically produce better results than adding unvalidated combination protocols
The 100mg cohort showed statistically significant reductions in visceral adipose tissue (8.3% vs baseline) and improvements in insulin sensitivity (HOMA-IR reduction of 18.7%), but no hepatotoxicity signals emerged across any dose tier