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As expected for enzymes that share the same co-substrate, some of the residues contributing to the recognition of GSH, Ser92 and Asp172, are conserved

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A 2013 review in Advances in Nutrition notes that several studies have found green tea extract to be beneficial for fat metabolism in both short- and long-term scenarios

With the most recommended safe strength of hydroquinone i.e 3%

The gradual onset allows the body to adapt to the medication whilst minimising adverse effects, particularly gastrointestinal symptoms that can occur with rapid dose escalation