Take Home Points Take Home Points PCOS is a highly complex and prevalent reproductive, endocrine, and metabolic disorder that needs to be detected and treated as early as possible to mitigate long-term complications Diet and physical activity should be the first line nutrition intervention for polycystic ovary syndrome (PCOS)
Emergence of Oral GLP-1 Agonists: Oral versions like Rybelsus are gaining popularity for improved patient adherence
For competitive athletes, hexarelin (also called examorelin) is explicitly named as a prohibited growth-hormone-releasing peptide under WADA's Prohibited List in category S2 (Peptide Hormones, Growth Factors, Related Substances and Mimetics), banned at all times as a non-specified substance carrying a default four-year sanction
Along this line, a recent large case-control study from 2024 including 162,253 obese patients treated with GLP-1 RAs and a matched group of untreated patients found an association between GLP-1 RAs and increased risk of depression, anxiety and suicidal behavior [10]
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