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Food and Drug Administration (FDA) for medical, therapeutic, diagnostic, or consumptive use
Clinical trial: insulin-sensitizing agents may reduce consequences of insulin resistance in individuals with nonalcoholic steatohepatitis
Key molecular mechanisms encompass oxidative modification of critical proteins leading to dysfunction [361], membrane lipid peroxidation disrupting organelle integrity [362], mtDNA damage causing mitochondrial dysfunction [363], and depletion of key antioxidant molecules [364]
Acknowledgements We thank all the participants of this study for providing their expert insights and perspectives
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