Week-by-Week Protocol Week 1: First Reta Dose Inject your starting dose (see table above) Note: food noise may temporarily return This is normalthe GIP ratio is different in retatrutide Week 2: Assessment If no new side effects: Bump by 0.5mg (if starting dose was under 2mg) Bump by 1mg (if starting dose was 2mg+) If experiencing glucagon-related effects (jitteriness, different hunger pattern, mild nausea): Stay at current dose another week Weeks 36: Find Your Effective Dose Continue titrating every 12 weeks Target: find the dose where satiety + energy feel stable Most people land between 36mg weekly for maintenance Week 6+: Maintenance Lock in your effective dose Adjust only if plateau lasts 3+ weeks What to Expect During Transition The First Two Weeks Food noise may return temporarily
Health care providers will have a variety of options when it comes to stopping a GLP-1 on how to continue seeing weight loss results in a way that works for you
The medication is given as a once-weekly injection under the skin
Buckley ST, Bkdal TA, Vegge A, Maarbjerg SJ, Pyke C, Ahnfelt-Rnne J, Madsen KG, Schele SG, Alanentalo T, Kirk RK, Pedersen BL, Skyggebjerg RB, Benie AJ, Strauss HM, Wahlund PO, Bjerregaard S, Farkas E, Fekete C, Sndergaard FL, Borregaard J, Hartoft-Nielsen ML, Knudsen LB
Ive seen patients feel completely different once we address the hormonal picture alongside the GLP-1. A third perspective: the new oral GLP-1 partial agonist entering the market may sidestep this entirely