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TL;DR Mounjaro (tirzepatide) side effects are primarily gastrointestinal: nausea affects roughly 25% of users and typically resolves within 48 weeks
In our wonderfully made bodies, after eating, the small intestine secretes the GLP-1 polypeptide hormone, a fixed sequence of 37 amino acid monomers
It starts before the first dose
Consistent with this, targeting nodes related to arginine metabolism, including the iNOS/arginase axis, may have potential therapeutic significance in inflammation- and autoimmune-related pathologies (53)
However, the transition to the clinic has been slow, and hunger, compliance, and health during fasting are also issues to consider
