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The SURMOUNT-4 trial demonstrated that participants who discontinued tirzepatide after initial weight loss regained approximately 14% of their body weight over 52 weeks, compared to those who continued treatment

People with pre-existing dry mouth conditions

[16] Only small amounts of choline are synthesized by the human body, necessitating its intake from external sources

39,43 In contrast, among HFpEF cohorts, semaglutide showed clinically meaningful benefits in non-diabetic and diabetic cohorts ( Table 1 )

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