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Prolonged use beyond 12 months Short-term semaglutide use of several months likely does not deplete b12 stores in people who start with adequate levels

Side effects are uncommon but may include mild discomfort or bruising at the injection site and occasional lightheadedness

Patients with regular usage of Mounjaro could lose an average of 20.2% of their body weight after using Tirzepatide for over 72 weeks when combined with healthy eating, followed by regular exercise How Long Does Mounjaro Take to Work

Patients planning long-term or indefinite semaglutide use should consider periodic b12 testing and supplementation if levels drop below optimal ranges

If youre concerned about pernicious anemia, ask your healthcare provider if youre at risk and what steps you can take to avoid vitamin B12 deficiency