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Thereafter, we investigated the antischistosomal activity and ability of the antioxidants N -acetylcysteine (NAC) and resveratrol (RESV) to augment the performance of praziquantel and/or artesunate (AS) against larval stages of the parasite

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Signalling-molecule effects: 1-methylnicotinamide is itself a signalling molecule

Hydro isn't off the table in these cases, but caution and close monitoring is needed