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Freezing a formulation that was not designed for it will likely destroy the medication

Medications included in the meta-analysis were tirzepatide (Zepbound, Eli Lilly), semaglutide (Wegovy, Novo Nordisk), liraglutide (Saxenda, Novo Nordisk), phentermine/topiramate (Qsymia, Vivus), naltrexone/bupropion (Contrave, Nalpropion Pharmaceuticals) and orlistat (Xenical, Roche)

That band is where most of the market lives, and it moved very little week to week

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A 2018 Ohio Medicaid audit found that PBMs retained $223.7 million in spread pricing on generic drugs over a single year, with some generics marked up by more than 1,000% over pharmacy acquisition cost