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Tirzepatide drops and tirzepatide tablet formulations are also in development, with Eli Lilly pursuing an oral tirzepatide that showed promising results in early trials

In pre-clinical studies, DA-1241 demonstrated a positive effect on liver inflammation, lipid metabolism, weight loss, and glucose metabolism, reducing hepatic steatosis, hepatic inflammation, and liver fibrosis, while also improving glucose control

However, also in mice, it has been reported that hypoglycemia produces a decrease in GH release [94, 95], most likely mediated by specific activation of neurons producing Neuropeptide Y [96]

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