CrossRef PP1A Modulates the Efficacy of Lenvatinib Plus ICIs Therapy by Inhibiting Ferroptosis in Hepatocellular Carcinoma Jitong Zhou, Meng Gao, Shikun Zhang, WingWa Guo, Wenzhi He, Minghe Zhang, Xi Chen, Cairang Dongzhi, Xiaomian Li, Yufeng Yuan, Weijie Ma Advanced Science .2025;[Epub] CrossRef Pathogenesis and Treatment of Hepatocellular Carcinoma Associated with Nonalcoholic Steatohepatitis Advances in Clinical Medicine .2025
Study on mechanisms of 3T3-L1 adipocyte differentiation promoted by GLP-1 mediated upregulation of LncRNA PFAR and its effect on obesity in mice [dissertation]
one example is through the suppression of the NOD-like receptor family, pyrin domain-containing 3 (NLRP3) inflammasome, which is an inflammatory complex containing three components, including NLRP3, caspase-1, and apoptosis-associated speck-like protein (ASC), resulting in the maturation and secretion of the proinflammatory cytokines Activation of the NLRP3 inflammasome plays an important role in high glucose-induced endothelial dysfunction in patients with type 2 diabetes mellitus and cardiovascular disorders
No dose adjustments are recommended for patients with hepatic impairment based on current evidence
And the third, involving two healthy people, simply showed that BPC-157 was well tolerated, with no adverse effects