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Mar 1 2019;109(3):597-605

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[23] Additionally, a 2018 observational study suggested an elevated risk of developing inflammatory bowel disease, specifically ulcerative colitis, which peaked after three to four years of use and decreased after more than four years

The Glp1r KO male mice (2428 g, 18- to 25-weeks-old) fed HFD for 3565 days, exhibited lesser degrees of obesity 53 but similar hyperglycemia