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Additionally, the appetite suppression often experienced with GLP-1 medications might lead to lower calorie intake, further contributing to fatigue

2014;4:e004885

While these typically do not require immediate intervention, they should be monitored, and patients should be counseled about symptoms that would necessitate treatment

32 The SOUL trial evaluated oral semaglutide in patients with T2D who had established atherosclerotic cardiovascular disease, chronic kidney disease (CKD), or both