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This is a particular issue for drug metabolizing enzymes, especially cytochrome P450, which are substantially downregulated [139]
Rajasekar, P., Palanisamy, N., and Anuradha, C
25 As an endocrine hormone, GLP-1 is secreted by enteroendocrine L-cells in the distal jejunum, ileum, and colon in response to food intake and neuroendocrine signals
Treatment is typically two-fold, involving home remedies and medical attention, especially for more severe cases
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