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Glucagon-like peptide-1 receptor agonists, but not dipeptidyl peptidase-4 inhibitors, reduce alcohol intake
Indeed, pancreatic nesidioblastosis (a hyperplasia of islet cells that is potentially driven by elevated secretion of GLP1) has been implicated in the pathogenesis of refractory hypoglycaemia
In the ELIXA [66], EXSCEL [68], and PIONEER 6 [67,71] studies, treatments of exenatide twice-daily, exenatide once-weekly, and oral semaglutide groups were non-inferior to placebo in terms of CV disease safety, respectively
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