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Sagara J et al
Nobiletin, a common natural flavonoid, has been found to activate mitophagy via AMPK and SIRT1 pathways, potentially alleviating D-galactose-induced mitochondrial damage in granulosa cells and delaying age-related apoptosis (Park et al., 2016
these take precedence over any general guidance
So, when we say glutathione is reduced, we mean it can remove oxygen or ROS hence its being an "antioxidant" after which the glutathione becomes oxidized
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