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What evidence would tell me this is working after 4 to 8 weeks

The jury is out at the moment, but their potential to be differentiated from injectable peptides is clear and seems likely to drive significant research into small molecule modulators of GLP-1 for the treatment of diabetes, obesity and perhaps addictive behaviours for many years to come.

Zeng T, Li J, Xie L, Dong Z, Chen Q, Huang S, Xie S, Lai Y, Li J, Yan W, Wang Y, Xie Z, Hu C, Zhang J, Kuang S, Song Y, Gao L, Lv Z (2023) Nrf2 regulates iron-dependent hippocampal synapses and functional connectivity damage in depression

The concentration was far below standard GHK-Cu serums (0.02% vs 1 to 2%)

A non-invasive laser treatment that gently heats the skin to stimulate collagen production and even out texture