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The transcriptional profiles of Bmp4 in the Hedgehog pathway showed downregulation by 4.53 folds, with Lep in the Insulin pathway being downregulated by 5.26 folds
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Neurology 92 , e1610e1623 (2019)
Notably, the highest dose tested (54 mg) showed increased gastrointestinal event frequency compared to lower doses, suggesting a dose-relationship for this effect category
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