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The most common treatment is lifelong B12 intramuscular injections although small amounts of B12 can be absorbed without intrinsic factor
In GPX5-gene KO mice, sperm DNA damage is significantly increased, while an 8-weeks pretreatment of GPX5 KO mice using antioxidants completely protects sperm DNA from oxidative stress damage ( 2.6 GPX6 Glutathione peroxidase 6 (GPX6), also known as olfactory organ glutathione peroxidase ( It is believed that GPX6 is mainly expressed in embryonic and olfactory organ epithelial cells, and may be involved in the transmission and degradation of odor-related signals
In healthy, resting cells, the ratio of reduced glutathione to oxidized glutathione is typically greater than 100:1
doi: 10.1159/000485044 155
Protecting Cells : By shielding cells from damage, antioxidants allow tissues to heal faster thereby reducing the long-term effects of chronic inflammation
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