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This model extends the model for one carbon metabolism in [20] by adding the transsulfuration pathway, the synthesis of glutathione, and its transport into the blood
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Maintenance schedule Month 1-2 : Stay at current dose, assess stability Month 3-4 : Reduce by 2.5mg, monitor weight Month 5-6 : Reduce again if weight stable Long-term : Minimum dose that prevents regain Coming off tirzepatide Not recommended : Abruptly stopping often leads to rapid weight regain
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