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Excretion of antidiuretic activity in the urine of cats and rats after administration of the synthetic hormonogen, N-glycyl-glycyl-glycyl-[8-lysine]-vasopressin (triglycylvasopressin)

Take-home perspective The central challenge in obesity management is no longer achieving weight loss, but maintaining it without sacrificing functional lean tissue

Discovery and development of dipeptidyl peptidase-4 inhibitors Dipeptidyl peptidase-4 inhibitors (DPP-4 inhibitors) are enzyme inhibitors that inhibit the enzyme dipeptidyl peptidase-4 (DPP-4)

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They all have the same basic mechanism they bind to the GLP-1 receptor in the body