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Most patients find these side effects are mild to moderate in severity and tend to diminish significantly after the first few weeks as the body adjusts to the medication
Antonie Van Leeuwenhoek 99 (4), 761771
With breach of the blood-brain barrier, immune cells infiltration as well as extravasation of blood-borne molecules such as fibronectin triggers, together with the death of oligodendrocytes, degeneration and transection of axons and starts a multicellular inflammatory response associated with reactive astro- and microgliosis
Wegovy should be discontinued at least two months before a planned pregnancy according to the SmPC
Interestingly, a study has shown that moderate coffee consumption (1 to 5 cups per day) is associated with a reduced risk of heart failure, type 2 diabetes (T2D), and chronic kidney disease (CKD) [65]
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