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10.1038/s41598-020-74200-y Sci Rep

A reduction in deaths occurred for patients supplemented with L-carnitine

The landmark 2017 Cell study (Baar MP et al., PMID: 28340339) demonstrated that: (1) FOXO4 protein specifically accumulates in senescent cells where it binds to p53 and prevents p53 from triggering apoptosis (this is the specific mechanism being targeted)