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First, its retrospective observational design precludes causal inference
Similarly, intermittent fasting requires careful consideration as it may disrupt hormonal balance in PCOS patients
MuraliManohar, S
Topiramate, propranolol, and valproate significantly reduced migraine frequency, intensity, and duration, consistent with the 2019 European Headache Federation guidelines, which classify topiramate and propranolol as Level A recommendations and valproate as Level B (Sacco et al., 2019)
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