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Common adverse effects are predominantly gastrointestinal and include: Nausea (reported in 1544% of patients) Vomiting (524%) Diarrhea (830%) Constipation (1124%) Abdominal pain (520%) These effects are typically most pronounced during initial treatment and dose escalation, often diminishing over several weeks as tolerance develops

The hormone shift during Tirzepatide therapy also affects protein synthesisthe biological process that builds new muscle fibers

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GLP-1 medications qualify for FSA reimbursement for weight management regardless of diabetes status, provided they are prescribed by a licensed healthcare provider