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A proposed two-phase stem cell model suggests copper-free GHK promotes stem cell replication and survival, while GHK-Cu (with copper) promotes differentiation
Exp eye Res (2015) 132:737
Also, the functionalization of PEG-RGD possessed GCMR NPs with further improved cytotoxicity (Figure 3B and Figure S8C ), which could be explained by the enhanced cellular uptake behavior
In the same study, glutamic pyruvate transaminase was five-fold higher in periportal hepatocytes versus centrilobular hepatocytes but increased in both areas of the lobule during a three-day fast
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