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ERRs are nuclear receptors involved in regulating genes associated with cellular energy production, oxidative metabolism, mitochondrial function, and physiological adaptation to energetic demands

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These physical properties make it suitable for various lab applications

How vitamin B12 works in the body Vitamin B12 works differently than other vitamins, in that a substance called intrinsic factor must be present in the intestinal tract in order for the body to absorb B12

Although this secondary analysis was not prospectively registered, both the exposure and outcomes were predefined based on those reported in the original trial, and the research question was based on a priori biological rationale