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Ubiquitination activity was dependent on a critical cysteine residue (C18) within the TRIM37 RING domain, 43 as TRIM37 C18R failed to catalyze TRIM28 ubiquitination in E
The constructed carrier-free indocyanine green nanoparticles (NanoICG) have smaller and more uniform sizes and better fluorescent performance compared to ICG molecules, without any molecular structure changes, and have demonstrated excellent imaging performance and effects in liver cancer surgery fluorescence navigation and lymph node imaging recognition
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The Kelch domain allows KEAP1 to interact with ubiquitin ligases of the Cullin family, specifically Cul3
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