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doi: 10.1073/pnas.0510033103 36 RommelCBodineSCClarkeBARossmanRNunezLStittTNet al

Additionally, the study aimed to explore the methyl-dependent epigenetic mechanisms that play a role in regulating these biomarkers as well as investigate the potential of vitamin B12 in modulating the gene expression of these genes in leukocytes

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Not only they are the major source or ROS within the cells, as they are also very susceptible to ROS-induced effects