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If disease activity remains inadequately controlled, treatment should escalate to combination conventional synthetic DMARDs or biological agents following a treat-to-target approach
This is relevant because muscle-related concerns with tirzepatide are common, and understanding how BMI category affects body composition changes helps set appropriate expectations
Kumar, D
Boal A, Ilhan F, DeRouchey J, Thurn-Albrecht T, Russell T, Rotello V
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