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doi:10.3390/nu6083259
When symptoms do occur, they usually reflect underlying conditionssuch as liver disease, haematological disorders, or renal impairmentrather than the elevated vitamin itself
It tested oral doses of 0.25, 0.5, or 1 mg per day against placebo
One study found that high doses of oral B12 (1,000 mcg daily) could provide adequate absorption even in the presence of intrinsic factor deficiency
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