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The supernatant was collected to quantify the amount of compound or substrate using LC-MS

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It is a gene-regulated and orderly process involving nuclear fragmentation, cytoplasmic shrinkage, and cell disassembly into apoptotic bodies [23, 24]

However if you start to feel unwell, or are worried you may not have successfully delivered your biologic medicine, contact your IBD team immediately - they will advise what to do next.

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