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Pharmacokinetic evaluations in humans report an approximate half-life of ~1 hour following subcutaneous administration, reflecting greater stability than native -MSH while remaining suitable for controlled research observation

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Heterogeneity was assessed using the I 2 statistic

Whether this should be regarded as specific metabolic treatment, targeting only the metabolic alterations of the syndrome, is debatable, since the improvement in metabolic conditions, e.g., insulin resistance, would tenably have a positive impact also in gonadal function in women with PCOS

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