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2c,d), and under dynamic glucose concentrations ranging from 2.7 to 16 mM glucose (Extended Data Fig

While RWE is inevitably limited by the possibility of residual confounding [16], we welcome the careful attention paid by the authors of EMPRISE to minimise possible sources of bias [16], such as the steps taken to address concerns relating to immortal time bias that have been raised with previous RWE studies [19,20,21], providing more confidence in its results

Future research should strive to unravel the specific roles ferroptosis plays in psoriasis and explore the possibility of managing the diseases inflammatory aspects by targeting the molecular mechanisms linked to ferroptosis

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If Mounjaro is commercially unavailable and listed on the FDA shortage list, our doctors may prescribe compounded tirzepatide, the active ingredient in Mounjaro , if deemed appropriate