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The most common side effects were mild and transient, including nausea, flushing, and headache (10%)
By increasing the rate at which fat is oxidized for energy, it not only aids in reducing fat stores but also helps maintain lean muscle mass, which is vital for a healthy metabolism
The compound then received GRAS (Generally Recognized as Safe) designation from the FDA for use as a food ingredient, which is a separate regulatory category from drug approval
Retatrutide, a not endogenously occurring peptide, stimulated the glucagon receptor (GCGR), the glucose-dependent insulinotropic polypeptide (GIP) receptor (GIPR), and the glucagon-like peptide-1 receptor (GLP-1R) in cell cultures
Ann Blood
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