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They also reduce hepatic glucose output by decreasing hepatic FFA uptake and the expression of key gluconeogenesis enzymes such as PEPCK and G6Pase, while promoting hepatic sensitivity to insulin, transforming the liver from an "energy output organ" to an "energy storage organ"
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Lipid panels often show modest improvement after weight loss and better glycemic control
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Graziano F, Renato B, Catalano V, and et al
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