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Abstract Objective Oxidative stress plays a pivotal role in the pathogenesis of Down syndrome (Trisomy 21), as chromosome 21 harbors multiple genes involved in redox homeostasis and antioxidant defense mechanisms

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doi:10.1001/jama.289.21.2827

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The key is prioritizing protein at every meal (15-20g minimum) and resistance training 2-3 times weekly

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