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It is important to distinguish between back pain that may be coincidental, related to the weight loss process itself, or potentially indicative of more serious complications such as pancreatitisa recognised adverse effect of GLP-1 receptor agonists
The GLP-1 receptor system is known to interact with central nervous system pathways involved in appetite regulation and arousal
A 2024 real-world study reported moderate weight loss, improved glycemia, and acceptable tolerability in adults with hypothalamic injury, though gastrointestinal side effects and variable response were noted [155]
GLP-1 medications are not approved as a replacement for insulin in type 1 diabetes
Based on simple randomization ( 2.3 Experimental design Animals were divided into 6 groups by simple randomization method, each group included 6 rats
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