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While the protection of normal cells against radiation-induced cell death by ebselen has been attributed to its ability to detoxify cellular/mitochondrial ROS through the GPx mechanism, the molecular mechanism contributing to its radio-sensitization effect in cancer cells is still not fully understood

Word Recognition Performance: Using standard 35-word lists in background noise, 40.2% of the active treatment cohort achieved a meaningful gain of 4 or more correctly recognized words, compared to 27.8% of the placebo cohort, representing a 12.4% net response rate

User 22 in our observational data highlighted this uncertainty when questioning if he really wanted to continue dosing twice daily in light of the 30-minute half-life

Finally, direct causal evidence in vivo remains limited