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Another limitation is ongoing monitoring
In the HARMONY study (n = 9463 patients with established coronary heart disease, cerebrovascular disease, or peripheral vascular disease), albiglutide, despite lowering MACE, had no effect on the risk of fatal or nonfatal stroke in the subgroup analysis during a follow-up of 1.6 years [18]
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A meta-analysis of Phase 3 trials reported HR increases in the range of 14 beats per minute (bpm) for exenatide twice daily (BID), exenatide long-acting release (LAR), and liraglutide [15]
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