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Compounded tirzepatide niacinamide should be stored in a refrigerator at 36 to 46 degrees Fahrenheit (2 to 8 degrees Celsius) immediately upon receipt
in darker skin types (Fitzpatrick III-VI), the risk of post-inflammatory hyperpigmentation (temporary darkening of the stain) or hypopigmentation (lightening) may be higher after procedures such as laser or chemical peeling
169 Therefore, the investigators have suggested switching to a non-oral contraceptive option or adding a barrier method of contraception for 4 weeks after tirzepatide administration is initiated or if the dose is substantially increased
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