"The 1440 nm and 1927 nm Nonablative Fractional Diode Laser: Current Trends and Future Directions," Journal of Drugs in Dermatology , August 2020.
What they found: In normal obese mice: AOD-9604 reduced body fat by 21 % vs placebo, hGH by 24 % The AOD-9604 effect was fully dependent on the 3-adrenergic receptor , in knock-out mice no effect The hGH effect was partly independent of 3-AR , in knock-out mice there was still ~10 % fat reduction AOD-9604 did not raise IGF-1 (control level), whereas hGH raised IGF-1 by 80 % No changes in growth, organ weights (except adipose tissue), fasting insulin Why it matters: The study provided the mechanistic basis for AOD-9604 and confirmed the key business hypothesis: it is possible to separate the lipolytic effect of GH from its growth effect
Rolando Grave de Peralta Menendez and Sara Gonzalez Andino developed the LAURA source estimation methods applied here, and Christoph Michel provided additional analysis software
It adds to oxidative stress, triggers apoptosis, and furthers the pathological progression of these conditions 3
Step 6: Draw the Solvent Using your sterile syringe and needle: Draw the calculated volume of bacteriostatic water into the syringe
