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If the drug remains expensive, it will only widen the gap

Carter J, Chang J, Birriel TJ, Moustarah F, Sogg S, Goodpaster K, Benson-Davies S, Chapmon K, Eisenberg D (2021) ASMBS position statement on preoperative patient optimization before metabolic and bariatric surgery

This legal pathway has existed for decades and applies to thousands of medications across all therapeutic categories

Other important safety considerations include hypoglycemia risk when combined with insulin or sulfonylureas, suicidal ideation (monitor for mood changes), and contraindication during pregnancy

When people are selected for a study based on symptoms, some of them tend to improve spontaneously over time (people often see a doctor and get recruited into studies when their symptoms are at their worst)