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IGF-1 is highly anabolic, meaning it promotes the growth and repair of muscle tissue
Pharmacological interventions are more limited, with antidepressants such as duloxetine (a serotonin-noradrenaline reuptake inhibitor) or amitriptyline (a tricyclic antidepressant) sometimes considered
doi: 10.1016/j.celrep.2019.06.018 42 JhaAKHuangSC-CSergushichevALampropoulouVIvanovaYLoginichevaEet al
How It Works (Step-by-Step) Take an online quiz to check eligibility Join and complete initial onboarding Get labs done and meet your coach Meet your clinician and start your plan Insurance team secures GLP-1 access Begin medication and curriculum Final labs and progress review at 12 months Geographic Availability Available in all 50 states Clinical Oversight and Safety US-licensed and board-certified clinicians oversee all care Lab work required early in the program and again at the end of the year Dose adjustments based on individual progress, insurance approval, and safety needs Communication with both clinicians and coaches via app Initial coaching begins within 1 week
In addition, the treatment response observed in our analysis may also be influenced by ethnic differences, given that five RCTs recruited exclusively Japanese participants [39,40,41, 48, 49]
