In a further exploration of the molecular mechanisms of this effect, it was revealed that GLP-1 increased hMSC proliferation, inhibited the process of their early adipogenesis, and reduced cell death in them
Wang X, Chen H, Han S, Li L, Chen H, Yang B
Gene and protein characterization of the human glutathione S-transferase kappa and evidence for a peroxisomal localization
HUBERMAN: It's also involved in any of the sort of downstream effects of having elevated LH and FSH, including elevated vitality, which includes both energy and in some cases, libido
The two datasets converge on the same point: much of what DXA labels as lean-mass loss on a GLP-1 is liver tissue responding to metabolic disease, not muscle responding to the medication