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Regarding the mechanism of action, is the GLP-1RA reducing lymphedema because of the induced weight loss or is there another mechanism at play

Retatrutide acts as a triple agonist targeting GIP, GLP-1, and glucagon receptors, producing weight loss averaging 24.2% in clinical trials

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Exceptions were observed when Liraglutide at 10 nM enhanced the proliferation of hMSC pretreated with LPS to mimic an inflammatory setting [4], and in experiments performed by Wang et al., where Liraglutide at 10 nM showed no effect on the proliferation of human bone marrow-derived stem cells (hBMSC) [21]