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A two-pronged nanostrategy of iron metabolism disruption to synergize tumor therapy by triggering the paraptosis-apoptosis hybrid pathway

To better mimic the complexity of the human brain, we differentiated brain organoids from iPSC of PSEN1-9 (depicted as AD-cBOs) and corresponding isogenic lines (depicted as Iso-cBOs) and studied whether ferroptosis-related proteins were altered in AD organoids

Chronic glutamate toxicity in neurodegenerative diseases-what is the evidence

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FoxO1 is involved in the antineoplastic effect of calorie restriction