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NNMT is involved in the conversion of nicotinamide, a form of vitamin B3, into methylated compounds

Last reviewed: May 12, 2026 Last updated: May 12, 2026 Written by: Jay Hastings , CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

I just think that is always in my mind of like, Is this safe for someone to do, and is this going to have any long-term effects? To Lennys point, theres one study in PFJ, like 7 of 12 patients reported subjective improvement in 6 months