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FOXO4-DRI is a senolytic peptide a D-retro-inverso peptide engineered to selectively eliminate senescent "zombie" cells that accumulate with age and secrete inflammatory factors (the senescence-associated secretory phenotype, or SASP)

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A variety of stressors can also influence its release, and the role of ACTH in the stress response is discussed later in this chapter

Chronic oxidative stress as a central mechanism for glucose toxicity in pancreatic islet beta cells in diabetes

Available from: National Institutes of Health, Office of Dietary Supplements